The Detroit Tigers used their first pick in 2007 on high school right-hander Rick Porcello. Porcello ascended rapidly through the minor leagues, making the opening day starting rotation in 2009 as a 20-year-old. He went 14-9 with a 3.96 ERA, finishing third in Rookie of the Year voting.
From 2010-2013, Porcello was a slightly below average, yet durable, starter for the Tigers. He went 47-41 with a 4.64 ERA, a 1.40 WHIP and a 90 ERA+. His low 5.6 K/9 and high 10.4 H/9 kept him from being anything more than a back-end starter.
2014 was Porcello’s most successful year in the Motor City. He posted the lowest walk-rate, hit-rate and WHIP of his career up to that point. That led to a tidy 3.43 ERA. He also had a league leading three shutouts, to date the only three of his career.
He struggled his first year in Boston, but more than made up for it by winning the Cy Young award in 2016 with a 22-4 record and a 3.15 ERA. Although his win was controversial (many felt Justin Verlander deserved the award) there is no doubt that Porcello was a successful first round pick by the Tigers.
Colorado Rockies second baseman DJ LeMahieu was drafted by the Tigers in the 41st round out of high school, but did not sign.